Biophysics

Understanding life at the molecular level through computation. Protein structure prediction, molecular dynamics simulation, and systems biology at a scale that was previously impossible.

Complete computational models of biological systems — from individual proteins to cellular machinery — that predict behavior, not just structure.

78%

Ensemble Accuracy

320x

MD Speedup

91.3%

EC Number Accuracy

0.87

Kinase Selectivity AUC

Focus Areas

Dynamic Structure

Beyond static folds — predicting conformational ensembles and how proteins move through their functional landscapes.

Millisecond Dynamics

Adaptive coarse-graining that achieves 85-320x speedups while preserving accuracy against experimental data.

Sequence to Function

Predicting what proteins actually do — enzymatic activity, binding specificity, and allosteric regulation from sequence alone.

Systems Biology

Modeling protein-protein interaction networks and cellular pathways at genome scale.

Publications

2026-03-05

Protein Structure Prediction in the Post-AlphaFold Era

What's left to solve in protein science — and how we're approaching the next frontier.

Webbeon Biophysics Team

2026-02-05

Molecular Dynamics at Millisecond Scale

Breaking the time-scale barrier in computational biology with ArcOne-accelerated simulation.

Webbeon Biophysics Team

2026-01-10

From Sequence to Function: Predicting What Proteins Actually Do

Beyond structure prediction — using frontier intelligence to understand protein behavior and biological function.

Webbeon Biophysics Team